Langerhans Cell Histiocytosis with Extensive Spinal and Thyroid Gland Involvement Presenting with Quadriparesis: An Unusual Case in an Adult Patient
- Author:
Mohd Ariff S
;
Joehaimey J
;
Ahmad Sabri O
;
Zulmi W
- Publication Type:Journal Article
- Keywords:
Langerhans Cell Histiocytosis, Spine Tumours, Thyroid Mass, Cord Compression With Quadriparesis, Adult
- From:Malaysian Orthopaedic Journal
2011;5(3):28-31
- CountryMalaysia
- Language:English
-
Abstract:
Langerhans cell histiocytosis of the spine frequently presents as a solitary lesion and rarely results in neurological deficit.
Involvement of thyroid tissue is also rare, even in multifocal disease presentations. We present an unusual variant of Langerhans cell histiocytosis in a 37-year-old man presenting with profound quadriparesis and incidental
thyroid involvement. MR imaging and skeletal radiographs
revealed widespread involvement of the spine. The patient
underwent surgical resection of the tumour and stabilization of the spine. Diagnosis was confirmed by histological and immunohistochemistry analysis. Langerhans cell histiocytosis should be included in the differential diagnosis of radiolucent lesions of the spine in adults.
- Full text:W020160108339168251578.pdf
