A Large Neuroendocrine Tumor of the Major Duodenal Papilla Removed by Endoscopic Papillectomy.
10.3904/kjm.2014.86.3.319
- Author:
Seung Hyeon BAE
1
;
Jin Yong KIM
;
Chang Lae KIM
;
Young Kwon CHOI
;
Bo Mi SHIN
;
Seung Mo HONG
;
Myung Hwan KIM
Author Information
1. Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. mhkim@amc.seoul.kr
- Publication Type:Case Report
- Keywords:
Neuroendocrine tumors;
Major duodenal papilla
- MeSH:
Adult;
Ampulla of Vater*;
Biopsy;
Diagnosis;
Duodenoscopy;
Endosonography;
Humans;
Male;
Natural History;
Neuroendocrine Tumors*
- From:Korean Journal of Medicine
2014;86(3):319-324
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Neuroendocrine tumors (NET) of the major duodenal papilla are rare and the natural history of this disease is not clear. We experienced a case in a 31-year-old male. Duodenoscopy revealed an enlarged major duodenal papilla with central umbilication and nodularity. Endoscopic ultrasonography (EUS) demonstrated a 3-cm hypoechoic mass that was confined to the submucosa. A biopsy led to the diagnosis of a grade 1 NET. The patient refused surgery, so we performed an endoscopic papillectomy. The tumor was removed completely. The resected specimen confirmed the diagnosis of a well-differentiated NET and all resection margins were negative. Surgical resection is currently considered to be the gold standard for the treatment of a large NET of the major duodenal papilla; however, endoscopic resection is a possible treatment modality for patients at high surgical risk or who are reluctant to undergo surgery.
