Pattern of hospital admission and outcome in Parkinson’s disease: A study from Punjab, India
- Author:
Birinder Singh Paul
;
Gunchan Paul
;
Gagandeep Singh
;
Sandeep Kaushal
;
Verma U
- Publication Type:Journal Article
- Keywords:
Parkinson’s disease;
hospital admission;
mortality
- From:Neurology Asia
2017;22(1):33-39
- CountryMalaysia
- Language:English
-
Abstract:
Background: The hospitalization rates of patients with Parkinson’s disease (PD) are 1.45 times higher
than for age matched controls. We studied the causes for admission, hospital course and outcomes in PD
population so that preventive measures could be developed. Methods: We prospectively studied patients
with the diagnosis of PD admitted to a tertiary care hospital in Ludhiana, India from January, 2012 to
December, 2014. Etiology for hospitalization was determined and the patients were divided into two
groups, admission due to causes related to PD or not associated with PD. The PD related admissions
were further categorized into Group I: directly disease related causes and Group II: indirectly disease
related causes. The primary outcome was mortality. The secondary outcome measures were duration
of hospitalization, requirement for ICU, need for mechanical ventilation and complications. Results:
There were 146 patients of PD out of 25,326 hospital admissions. Forty two patients (28.7%) had
direct cause, 73(50%) had indirect cause and 31(21.2%) were non-PD related admissions. The mean
age was 68.5+9.9 years, 97males (66.7%). There were 16(10.9%) deaths. The commonest cause of
admission was infections and encephalopathy. The indirect PD related admission had significantly
higher age (p= 0.0014), increased risk of ICU admission (p=0.011), need for mechanical ventilation
(p < 0.005) and longer duration of hospital stay (p=0.0001) as compared to group I. Also there was
a six fold increased risk of death in this group (p 0.034).
Conclusion: As disease progresses, the indirect reasons for admission becomes more troublesome
than the initial motor complaints.
- Full text:P020170413320267436151.pdf
