Paraneoplastic Neurological Disorder in Nasopharyngeal Carcinoma
- Author:
Sze Yin Ng
;
Min Han Kong
;
Mohd Razif Mohamad Yunus
- Publication Type:Journal Article
- Keywords:
nasopharyngeal carcinoma, neurological disorder, paraneoplastic syndrome, nervous system,
- From:Malaysian Journal of Medical Sciences
2017;24(1):113-116
- CountryMalaysia
- Language:English
-
Abstract:
Paraneoplastic neurological disorder (PND) is a condition due to immune cross-reactivity
between the tumour cells and the normal tissue, whereby the “onconeural” antibodies attack the
normal host nervous system. It can present within weeks to months before or after the diagnosis
of malignancies. Nasopharyngeal carcinoma is associated with paraneoplastic syndrome, for
example, dermatomyositis, and rarely with a neurological disorder. We report on a case of
nasopharyngeal carcinoma with probable PND. Otolaryngologists, oncologists and neurologists
need to be aware of this condition in order to make an accurate diagnosis and to provide prompt
treatment.
- Full text:P020170313584203199100.pdf
