Ankle-brachial index as a predictor of one-year prognosis in ischemic stroke patients
- Author:
Hyun Goo Kang
;
In Sung Choo
;
Bum Joon Kim
;
Seong Hwan Ahn
- Publication Type:Journal Article
- Keywords:
Stroke
- MeSH:
Atherosclerosis;
Peripheral arterial disease;
Stroke
- From:Neurology Asia
2016;21(3):217-224
- CountryMalaysia
- Language:English
-
Abstract:
Objective: Peripheral arterial disease (PAD) reduces functional activity and increases the rate of
cardiovascular death in the elderly. Our study aimed to determine whether the presence of PAD in
stroke patients affected the progression of disability or death one year after discharge. Methods: From
April 2012 to March 2013, consecutive first stroke patients above 50 years of age without known PAD
were enrolled. PAD was defined as a low ankle-brachial index (less than 0.9) measured by an automatic
device. Clinical data associated with the stroke were collected from medical records. Disability in stroke
patients was evaluated with the modified Rankin scale (mRS) on discharge day and one year after the
index stroke. Progression of disability was defined as an increase in mRS more than one level at one
year. Results: Among the 526 patients, 238 had ischemic strokes and underwent ankle-brachial index
(ABI) measurement. Of them, 192 patients were included. In univariate analysis, age, dyslipidemia,
discharge mRS, low-density lipoprotein cholesterol, D-dimer, homocysteine, internal carotid artery
stenosis, posterior cerebral artery stenosis, and PAD were factors associated with worsening mRS.
After adjustment for these factors in the logistic regression analysis, PAD was an independent factor
associated with worsening mRS. In the analysis of one-year mortality, patients with PAD had a higher
death rate, but PAD was not an independent factor after adjusting for other variables.
Conclusions: The presence of PAD in stroke patients suggests a chance of disability progression, but
may not be a predictor of death after one year.
- Full text:P020161014306015582808.pdf
