Median Survival Time of Endometrial Cancer Patients with Lymphovascular Invasion at the Hospital Universiti Sains Malaysia
- Author:
Wan Adnan Wan Nor Asyikeen
;
Ab Hamid Siti-Azrin
;
Nur Asyilla Che Jalil
;
Anani Aila Mat Zin
;
Nor Hayati Othman
- Publication Type:Journal Article
- Keywords:
endometrial carcinoma;
female;
retrospective study;
Kaplan-Meier estimate;
Malaysia
- From:Malaysian Journal of Medical Sciences
2016;23(6):44-51
- CountryMalaysia
- Language:English
-
Abstract:
Background: Endometrial cancer is the most common gynaecologic malignancy among
females worldwide. The purpose of this study was to determine the median survival time of
endometrial cancer patients at the Hospital Universiti Sains Malaysia (USM).
Methods: A list of 121 endometrial cancer cases registered at Hospital USM between 2000
until 2011 was retrospectively reviewed. The survival time of the endometrial cancer patients
was estimated by Kaplan-Meier survival analysis. Log-rank tests were performed to compare the
survival of the patients based on socio-demographics and clinical presentation.
Results: Only 108 patients, 87.0%, were included who were of Malay ethnicity. Previous
history included menopause in 67.6% of patients and diabetes mellitus in 39.8% of patients;
additionally, 63.4% of patients were nulliparous. Tumour staging was as follows: 24.5% stage
I, 10.8% stage II, 26.5% stage III and 38.2% stage IV. The overall median survival time of the
endometrial cancer patients was 70.20 months (95% confidence interval (CI): 51.79, 88.61). The
significant factors were age, the presence of lymphovascular invasion and treatment received.
Conclusion: The overall survival of endometrial cancer was low. A prospective study
needs to be carried out to discover more effective and accurate tests for the early detection of
endometrial cancer.
- Full text:P020170717525930882206.pdf
