Spontaneous remission without progression to limbic encephalitis in a patient with LGi1 seropositive faciobrachial dystonic seizure
- Author:
Sherrini Bazir Ahmad
;
Suhailah Abdullah
;
Chong Tin Tan
;
Kheng Seang Lim
;
Khean Jin Goh
- Publication Type:Case Reports
- Keywords:
Faciobrachial dystonic;
pathognomonic
- MeSH:
Limbic Encephalitis
- From:Neurology Asia
2016;21(2):191-193
- CountryMalaysia
- Language:English
-
Abstract:
Faciobrachial dystonic seizures are pathognomonic of leucine-rich glioma inactivated-1 (LGi1)
antibody, non-paraneoplastic limbic encephalitis. Faciobrachial dystonic seizures usually precede
limbic encephalitis by about a month. It is unknown whether, if untreated, faciobrachial dystonic
seizures inevitably progress to limbic encephalitis. We present an LGi1 seropositive patient with
a year’s history of faciobrachial dystonic seizures, who achieved remission spontaneously without
immunotherapy or antiepileptic drug treatment, and did not develop evidence of limbic encephalitis
over a three-year follow-up.
- Full text:P020160714416818486528.pdf