Importance of proper window setting in visual assessment of dopamine transporter imaging: A case of early-onset Parkinsonism related to Park2 gene mutation
- Author:
Aryun Kim
;
Han-Joon Kim
;
Beomseok Jeon
- Publication Type:Case Reports
- MeSH:
Parkinson Disease
- From:Neurology Asia
2016;21(2):187-189
- CountryMalaysia
- Language:English
-
Abstract:
In the early stages or atypical manifestation of parkinsonism, dopamine transporter imaging can assist
the early diagnosis. We describe a 19 year-old man presenting with progressive gait disturbance,
cervical dystonia and head tremor. 18F-FP-CIT PET (FluoroPropyl-Carbomethoxylodopropyl-nor-BTropane
positron emission tomography) was done and interpreted as normal at other hospital, and his
diagnosis remained baffling. He visited our hospital several months later, and the FP-CIT PET image
was reviewed by the nuclear medicine physician in our hospital, who also interpreted it as normal.
However, we reviewed his FP CIT-PET image because his clinical picture was strongly suggestive of
juvenile parkinsonism. After adjusting the window setting of the PET image, we could appreciate the
decreased uptake in the bilateral basal ganglia. Thus he was finally diagnosed as juvenile parkinsonism
and gene test confirmed Park2 gene mutation. In conclusion, proper window setting is important during
visual assessment of dopamine transporter imaging.
- Full text:P020160714413004739190.pdf
