Prevalence of pain and depression and their coexistence in patients with early stage of Parkinson’s disease
- Author:
Shinji Ohara
;
Ryoichi Hayashi
;
Katsuhiko Kayanuma
;
Harumi Kuwabara
;
Kotaro Aizawa
;
Hiroshi Koshihara
;
Kenya Oguchi
;
Yo-ichi Takei
;
Naoko Tachibana
- Publication Type:Review
- MeSH:
Parkinson Disease
- From:Neurology Asia
2015;20(4):355-361
- CountryMalaysia
- Language:English
-
Abstract:
Depression and pain are common and often early non-motor symptoms of Parkinson disease (PD).
The relationship between pain and depression in PD has been unsettled, with conflicting findings.
The PD patients followed up at the general neurology outpatient clinics were requested to complete
Beck Depression Inventory (BDI) and McGill pain questionnaire. The patients were categorized in
three groups according to the Hoehn-Yahr (H-Y) stage of PD; mild (stage I&II), moderate (stage III)
and advanced stage (stage IV&V), and group comparisons were performed in each group between
those with and without pain. A total of 186 patients completed the questionnaires. Their mean age was
74±9.3 years, and the mean H-Y stage was 2.8±0.8.Sixty-nine percent of the patients reported pain
symptoms of various natures. The BDI scores were significantly higher in the pain group (P< 0.0001)
despite the absence of statistically significant differences in the mean age, H-Y stage, and duration of
illness. Only PD patients of mild stage revealed significant difference of BDI scores between those
with pain and without pain (P <0.001). Our results showed that pain is a common symptom in patients
with PD and suggest that it may be related to depression in the early stage of the disease.
- Full text:P020160302342006848894.pdf
