Association between the Gensini Score and Carotid Artery Stenosis.
10.4070/kcj.2016.46.5.639
- Author:
Anil AVCI
1
;
Serdar FIDAN
;
Mehmet Mustafa TABAKÇI
;
Cuneyt TOPRAK
;
Elnur ALIZADE
;
Emrah ACAR
;
Emrah BAYAM
;
Muhammet TELLICE
;
Abdurrahman NASER
;
Ramazan KARGIN
Author Information
1. Deparment of Cardiology, 1-Kartal Koşuyolu Cardiovascular Research and Training Hospital, Istanbul, Turkey. dr_kouyolu@yahoo.com
- Publication Type:Original Article
- Keywords:
Coronary atherosclerosis;
Carotid artery disease;
Doppler ultrasonography
- MeSH:
Carotid Arteries*;
Carotid Artery Diseases;
Carotid Stenosis*;
Constriction, Pathologic;
Coronary Artery Bypass;
Coronary Artery Disease;
Coronary Occlusion;
Coronary Vessels;
Humans;
Male;
Retrospective Studies;
Risk Factors;
Ultrasonography;
Ultrasonography, Doppler
- From:Korean Circulation Journal
2016;46(5):639-645
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND AND OBJECTIVES: The aim of this study was to evaluate the association between the extent of coronary artery disease assessed by the Gensini score and/or the SYNTAX score and the significant carotid stenosis in patients undergoing coronary artery bypass grafting (CABG). SUBJECTS AND METHODS: A total of 225 patients who had carotid doppler ultrasonography prior to CABG were included retrospectively. Significant coronary artery disease was assumed as a lumen diameter stenosis of ≥50% in any of the major epicardial coronary arteries. The severity of carotid stenosis was determined by B-mode and duplex ultrasonography. Clinically significant carotid stenosis was defined as peak systolic velocity greater than 125 cm/s. RESULTS: The mean value of SYNTAX score and Gensini score was highest in patients allocated to significant carotid stenosis (22.98±7.32, p<0.001 and 77.40±32.35, p<0.001, respectively). The other risk factors for significant carotid stenosis were found to be male gender (p=0.029), carotid bruit (p<0.001), diabetes (p=0.021), left main disease (p=0.002), 3-vessel disease (p=0.008), chronic total coronary occlusion (p=0.001), and coronary artery calcification (p=0.001) in univariate analysis. However, only the Gensini score (odds ratio[OR]=1.030, p=0.004), carotid bruit (OR=0.068, p<0.001), and male gender (OR=0.190, p=0.003) were the independent predictors. The Gensini score cut off value predicting significant carotid stenosis was 50.5 with 77% sensitivity (p<0.001). CONCLUSION: The Gensini score may be used to identify patients at high risk for significant carotid stenosis prior to CABG.
