Free amino acids differential analysis between breast cancer and mammary glandular tissues

VernacularTitle:乳腺癌癌肿组织与癌旁乳腺组织游离氨基酸差异性分析
Author: Fuqiao WEI ; Qingxiang SHEN ; Wenbiao XIE
Publication Type:Journal Article
Keywords: Tissue free amino acids; Cancer tissue; Mammary gland tissue
From: Journal of Endocrine Surgery 2010;04(5):307-308,313
CountryChina
Language:Chinese
Abstract: Objective To assay free amino acids (FAA) content of breast cancer tissue and mammary glandular tissue and discuss the therapeutic basis of unbalanced amino acids of breast cancer. Methods The selected samples were conserved and then cut into pieces, grinded, syruped and deproteinized. Then FAA were separated from the samples. The content of 17 kinds of free amino acids in breast cancer tissue and mammary glandular were assayed respectively. Results The concentration of FAA in breast cancer tissue was higher than that in mammary glandular tissue. Conclusions Free amino acids metabolism was greatly different in breast cancer and mammary glandular tissues. This offers a therapeutic basis for the treatment of unbalanced free amino acids in the case of breast cancer.