THE RELATIONSHIP BETWEEN THE SPONTANEOUS NOCTURNALEPISODES OF ALKALINIZATION AND AUTONOMIC NERVOUSFUNCTION ON FD PATIENTS
- Author:
Ru ZHANG
;
Jun GONG
;
Anqi SONG
;
Lei WANG
;
Xueqin WANG
;
Youling ZHU
- Publication Type:Journal Article
- Keywords:
gastric;
pH monitoring;
heart rate variability;
vagal function
- From:
Journal of Pharmaceutical Analysis
2000;12(1):37-39,66
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relationship between the spontaneous nocturnal episodes of alkalinization and the autonomic nerve system function and vagal function. Methods 24-hour intragastric pH was measured and auto nomic and vagal function was measured with the time domain analyses of heart rate variability in 20 patients with functional dyspepsia but without diseases of the cardiovascular system. Results 13 of 20 had the nocturnal episodes of alkalinization. The total 24-hour SDNN and rMSSD were normal in 20 subjects with FD. There was no significant dif ference (P ＞0. 05) in the comparison of the total SDNN and rMSSD of the 2 groups with alkalinization and without alkalinization. The 2 groups both had higher PNN50s in the nocturnal time, and there was no significant difference (P ＞0. 05). Conclusion The results suggest that the total autonomic nerve function and vagal function of patients with FD are normal, vagal activities of the 2 groups are both increased in the nocturnal period. The reason for the nocturnal episodes of alkalinization is not a decrease of vagal activity with a subsequent decrease of secretion.
