STUDIES ON THE RELATIONSHIP BETWEEN SUBSTANCE P AND ABNORMAL GASTROINTESTIANL TRANSIT
- Author:
Shuqin ZHAN
;
Jinyan LUO
;
Jun GONG
;
Xinkui GUO
- Publication Type:Journal Article
- Keywords:
substance P;
abnormal gastrointestinal transit;
radioimmunoassay
- From:
Journal of Pharmaceutical Analysis
2000;12(2):146-147,167
- CountryChina
- Language:Chinese
-
Abstract:
Objective To realize the relationship between substance P(SP) and abnormal gastrointestinal tran- sit. Methods By radioimmunoassay, concentration of SP in sigmoid mucosa was determined in 12 healthy volun- teers, 15 slow and 10 fast transit patients. ResultsThe concentration was (27.68±15.42)μg/g, (24.07+5.76)μg/g and (28.61± 18.34)μg/g,respectively. They had no statistical difference. Conclusion There was no relationship be- tween concentration of SP in sigmoid mucosa and abnormal gastrointestinal transit.
