Acute Hyponatremia With Seizure and Mental Change After Oral Sodium Picosulfate/Magnesium Citrate Bowel Preparation.
- Author:
Young Sun CHO
1
;
Kyung Min NAM
;
Jang Ho PARK
;
Sang Hwan BYUN
;
Jin Suck RYU
;
Hyun Ju KIM
Author Information
- Publication Type:Case Report
- Keywords: Picosulfate sodium; Bowel preparation; Hyponatremia; Seizures; Colonoscopy
- MeSH: Aged; Citric Acid*; Colon; Colonoscopy; Dementia; Diagnosis; Female; Humans; Hypertension; Hyponatremia*; Hypothyroidism; Injections, Intravenous; Rectum; Seizures*; Sodium*; Thyroxine; Unconsciousness
- From:Annals of Coloproctology 2014;30(6):290-293
- CountryRepublic of Korea
- Language:English
- Abstract: Sodium picosulfate/magnesium citrate (Picolight Powder), which is used as a bowel preparation for the colon and the rectum, can cause a severe electrolyte imbalance like hyponatremia. When hyponatremia gets severe or occurs rapidly, it can lead to death due to associated complications. We have experienced a case of hyponatremia associated with seizure and loss of consciousness in a 76-year-old woman, who took sodium picosulfate/magnesium citrate as a bowel preparation for colonoscopy. She was taking thiazide and synthroid for the treatment of hypertension and hypothyroidism, respectively, and she had other underlying medical conditions such as a history of seizure and dementia. Following the diagnosis of hyponatremia, we used an intravenous injection of 3% NaCl to normalize the sodium level in her serum, and her associated symptoms soon disappeared.