Identification of Erysipelothrix rhusiopathiae by DNA Sequencing in a Culture-Negative Intra-Abdominal Abscess.
10.5145/ACM.2014.17.4.132
- Author:
Hee Jae HUH
1
;
Hyun Young KIM
;
Young Eun HA
;
Chang Seok KI
;
Nam Yong LEE
Author Information
1. Department of Laboratory Medicine & Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. micro.lee@samsung.com
- Publication Type:Case Report
- Keywords:
Abscess;
Erysipelothrix rhusiopathiae;
Sequencing;
16S rRNA
- MeSH:
Abdominal Abscess*;
Abdominal Pain;
Abscess;
Aged;
Alcoholism;
Animals;
Anti-Bacterial Agents;
Bacillus;
Bacteria;
Erysipelothrix*;
Humans;
Sequence Analysis, DNA*
- From:Annals of Clinical Microbiology
2014;17(4):132-135
- CountryRepublic of Korea
- Language:English
-
Abstract:
Erysipelothrix rhusiopathiae is a Gram-positive bacillus that causes infections primarily in animals. In humans, the bacteria usually cause localized or generalized cutaneous infections. A 75-year-old man with chronic alcoholism presented with abdominal pain. Abdominal computed tomography and laboratory findings suggested an intra-abdominal abscess in the periaortic soft tissue. While no definitive infectious source was identified, E. rhusiopathiae was identified by 16S rRNA-based gene sequencing from culture-negative, periaortic necrotic tissue, subsequent to empiric antibiotic treatment. It is suggested that E. rhusiopathiae has the potential to cause intra-abdominal abscesses. This case report highlights the usefulness of DNA sequencing to identify pathogens in patients pretreated with antibiotics.
