Sentinel lymph node biopsy replaces axillary lymph node dissection for patients with early breast cancer

VernacularTitle:早期乳腺癌前哨淋巴结活检术替代腋窝淋巴结清扫术的临床研究
Author: Yinghua LI ; Chunlong GUO ; Jian JIANG ; Guixin WANG ; Caigang LIU ; Haidong ZHAO
Publication Type:Journal Article
Keywords: Breast cancer; Sentinel lymph node biopsy; Axillary lymph nodes cleaning
From: Journal of Endocrine Surgery 2015;(2):106-108,135
CountryChina
Language:Chinese
Abstract: Objective To study the application value and safety of sentinel lymph node biopsy ( SLNB) replacing axillary lymph node dissection ( ALND) for patients with early breast cancer .Methods Data was col-lected for patients undergoing SLNB or ALND in the Second Hospital of Dalian Medical University from June 2011 to June 2014.The complication of upper extremity , axillary local recurrence and distant metastasis were retro-spectively analyzed.The patients were followed up to Nov .2014, with the median follow-up of 41 ( 18-52 ) months.Results Patients undergoing SLNB had less postoperative complications of upper extremity ( numb and painχ2 =18.174, P =0.000;Restricted movement χ2 =20.413, P =0.000; Strength loss χ2 =23.785, P =0.000;P<0.05).There was no statistical difference for the postoperative complications of axillary local recur-rence and distant metastasis (χ2 =0.555, P=0.516; P>0.05).Conclusion In early breast cancer without SLN, SLNB can achieve the equivalent effect to ALND with less damage and complications .