Application of the detection of heart fatty acid-binding protein to early diagnostic of myocardial injury
- VernacularTitle:心肌型脂肪酸结合蛋白在诊断早期心肌损伤的应用及法医学意义
- Author:
Miao GUO
;
Lihua WAN
- Publication Type:Journal Article
- Keywords:
H-FABP;
Myocardial injury;
Sudden cardiac death;
Forensic science
- From:
Chinese Journal of Medical Education Research
2006;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Heart fatty-acid-binding protein(H-FABP) is small molecular weight cytosolic protein that is abundant in the heart and has tissue specificity. Concentration of H-FABP changes regulation in serum after the myocardial damage. In addition it has a positive correlation with the degree of myocardial damage. It is an early diagnostic biochemical marker of acute myocardial ischemia. The advance of H-FABP in the research on physiochemical nature,and its application for myocardial injury and prospective study of sudden cardiac death in forensic science were reviews.
