Mean Sojourn Time of Preclinical Gastric Cancer in Korean Men: A Retrospective Observational Study.
10.3961/jpmph.2014.47.4.201
- Author:
Jong Myon BAE
1
;
Sang Yop SHIN
;
Eun Hee KIM
Author Information
1. Department of Preventive Medicine, Jeju National University School of Medicine, Jeju, Korea. jmbae@jejunu.ac.kr
- Publication Type:Original Article ; Research Support, Non-U.S. Gov't
- Keywords:
Stomach neoplasms;
Early detection of cancer;
Mass screening;
Gastroscopy;
Gastrointestinal endoscopy;
Korea
- MeSH:
Adult;
Aged;
*Algorithms;
Asian Continental Ancestry Group;
Cohort Studies;
Early Detection of Cancer;
Gastroscopy;
Humans;
Incidence;
Male;
Mass Screening;
Middle Aged;
Republic of Korea;
Retrospective Studies;
Stomach Neoplasms/*epidemiology/pathology;
Time Factors
- From:Journal of Preventive Medicine and Public Health
2014;47(4):201-205
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVES: This retrospective cohort study aimed to estimate the mean sojourn time (MST) of preclinical gastric cancer in Korean men. METHODS: The subjects consisted of voluntary male screenees aged 40 to 69 years who underwent subsequent screening gastroscopies after testing negative at a baseline screening performed between January 2007 and December 2011. A new case was defined if gastric cancer cells were present in the biopsy specimens obtained from gastroscopy. The follow-up period was calculated as the number of person-years between the date of baseline screening gastroscopy and positive findings at a subsequent screening. The MST was calculated using transition rates of gastric cancer to determine the best screening interval. RESULTS: Of the 171 979 voluntary male screenees, 61 688 (36%) underwent subsequent screening gastroscopies between January 2007 and December 2011. A total of 91 incident cases were found during 19 598 598 person-years of follow-up. The MST of gastric cancer was 2.37 years (95% confidence intervals, 1.92 to 2.96), and those aged 40 to 49 years had a shorter MST than those 50 to 69 years did. CONCLUSIONS: These findings support the 2-year interval of screening recommended by the nationwide gastric cancer screening program in Korea. Further studies for the age-specific MST among women are needed.
