Effect of intensive insulin therapy on short-term prognosis of severe chest trauma patients

VernacularTitle:强化胰岛素治疗对严重胸部创伤患者近期预后的影响
Author: Chengjun LIU ; Weibin LIU ; Quanming SUN ; Shengping ZHANG
Publication Type:Journal Article
Keywords: Severe chest trauma; Intensive insulin therapy; Prognosis
From: Journal of Endocrine Surgery 2012;06(3):185-187
CountryChina
Language:Chinese
Abstract: Objective To observe the effect of intensive insulin therapy (ⅡT) on prognosis of severe chest trauma (SCT) pateints.Methods 42 consecutive patients were randomly assigned to 2 groups:ⅡT group (n =21) and the conventional insulin therapy group (CIT group,n =21).Blood glucose was maintained at the level of 4.4 -6.1mmol/L in ⅡT group,and 10.0 -11.1mmol/L in CIT group.The 2 groups were observed in terms of fatality rate during hospital stay,infection rate,the duration of mechanical ventilation,ICU stay length,pleural drainage day and count of neutrophils.Results No death or hypoglycemic reaction happened during hospitalization.Compared to CIT group,infenction rate,mechanical ventilation time,ICU stay length,and the time required for white blood cell to resume normal in ⅡT group were decreased significantly ( P ＜ 0.05 ).The difference had no statistical significance between the 2 groups in duration of pleural drainage and incidence of hypoglycemia (P ＞ 0.05).Conclusion ⅡT improves the short-term prognosis of SCT patients.