Calcification in differential diagnosis of thyroid nodules
10.3760/cma.j.issn.1674-6090.2014.04.017
- VernacularTitle:钙化在甲状腺结节鉴别诊断中的意义
- Author:
Wenxian DING
;
Haizhou SHI
- Publication Type:Journal Article
- Keywords:
Calcification;
Thyroid nodules;
Ultrasonography;
Pathology
- From:
Journal of Endocrine Surgery
2014;(4):316-318
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the significance of calcification in diagnosis of thyroid mass , and to improve the differential diagnosis of benign and malignant thyroid nodules .Methods 286 cases with thyroid masses admitted to the hospital from Jan .2008 to Dec.2012 underwent preoperative ultrasound scan .The clinical data were retrospectively analyzed from patients with or without calcification , the characteristics of different calci-fication and the comparison between preoperative diagnosis and postoperative pathological results .Results Ultra-sound and pathological analysis showed there was significant difference between calcification group and non -calci-fication group in detection rate of thyroid cancer (66.98%vs 13.51%, P<0.05).Detection rate of thyroid car-cinoma was significantly higher in microcalcification group than in coarse calcification group ( 84.42% vs 20.69%,P<0.05) .There was significant difference in detection rate of benign and malignant nodules in the two types of calcification group(P<0.05).The detection rate was higher in the malignant nodules than in the benign nodules .The detection rate of thyroid cancer had no statistical significance in non-calcification group and coarse calcification group ( P>0.05 ) .Conclusion Thyroid calcification , especially microcalcification has important significance in diagnosis of thyroid cancer .