Value of 99 Tcm-MIBI tomography and integrated CT scan in preoperative localization diagnosis of prima-ry hyperparathyroidism
10.3760/cma.j.issn.1674-6090.2014.04.019
- VernacularTitle:99 Tcm-MIBI 断层及 CT 融合显像在甲状旁腺功能亢进症术前定位诊断中的价值
- Author:
Changming ZHANG
;
Hongyan ZHAI
;
Ying ZHANG
;
Yufang ZHANG
- Publication Type:Journal Article
- Keywords:
Primary hyperparathyroidism;
Technetium (99 Tcm ) methoxy isobutyl isonitrile;
Single photon emission computed tomography;
Fusion imaging
- From:
Journal of Endocrine Surgery
2014;(4):322-324
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the value of technetium-99m methoxy isobutyl isonitrile(99Tcm-MIBI) tomography and integrated CT scan in preoperative localization diagnosis of primary hyperparathyroidism (PHPT). Methods 31 patients with PHPT were selected .15 minutes and 90 minutes ( delayed images ) after intravenous administration of 99 Tcm-MIBI 370 MBq, static anterior planar images of the neck and chest were obtained .99 Tcm-MIBI tomography and integrated CT scan were acquired after the delayed images .All patients received neck ultra-sound scan before surgery .The imaging findings were compared to the pathological results .Results The detec-tion rate of hyperparathyroidism lesions of 99 Tcm-MIBI dual-phase imaging and 99 Tcm-MIBI tomography and regis-tration with integrated CT scan was 87.1%and 93.5%respectively, without statistical significance (P>0.05). However , they were both higher than ultrasound scan which had a detection rate of 64.5%.The differences had statistical significance (χ2 =4.039 and 7.884 respectively , P<0.05 ) .The detection rate of parathyroid hyper-plasia of 99 Tcm-MIBI tomography and registration with integrated CT was both 80.0%, higher than that of the ul-trasound test(40.0%)and 99Tcm-MIBI dual-phase imaging(40.0%).The fusion imaging with integrated CT scan provided detailed anatomy data and more information for surgical doctors .Conclusions 99 Tcm-MIBI tomography and registration with integrated CT scan can improve the detection rate of PHPT compared with 99 Tcm-MIBI dual-phase imaging , provide detailed anatomy data , and has high clinical value in preoperative localization diagnosis of PHPT.
