Diagnosis and treatment of primary hyperparathyroidism initially with urinary calculus
10.3760/cma.j.issn.1674-6090.2014.04.020
- VernacularTitle:以泌尿系结石首发的原发性甲状旁腺功能亢进症的诊治分析
- Author:
Junkai CHANG
;
Kanda FU
;
Qingnan XIE
;
Weibo XU
;
Wenchao XU
;
Junqing HOU
;
Hui LIU
;
Xinyi DU
- Publication Type:Journal Article
- Keywords:
Calculus;
Hyperparathyroidism;
Surgical procedures
- From:
Journal of Endocrine Surgery
2014;(4):325-327
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the diagnosis and treatment of primary hyperparathyroidism ( PHPT) initially with urinary calculus .Methods The clinical data of 26 patients who diagnosed as PHPT ini-tially with urinary calculus were retrospectively reviewed .Results There were 22 cases with bilateral urinary calculus and 4 cases with unilateral relapsed urinary calculus .Ultrasonography , CT and radionuclide were helpful to determine the location of the neoplasia .24 cases underwent percutaneous nephroscope or ureteroscopy pneu-matic ballistic lithotripsy , 2 cases discharged ureteral calculi by themselves .All patients were performed surgical treatment of PHPT , which was confirmed by intraoperative frozen pathology and postoperative pathological exami -nation.There was great improvement of clinical symptoms after surgical procedures .The preoperative serum calci-um, urine calcium and parathyroid hormone elevated , while serum phosphate decreased .The postoperative indi-cators were just the opposite .The difference had statistical significance ( P<0.05 ) .Conclusions Laboratory investigations and imaging studies are very important to diagnose PHPT initially with urinary calculus .The para-thyroid surgery can remarkably reduce the calculus recurrence and improve renal function .
