Neoadjuvant chemotherapy for breast cancer and it's non-randomized clinical observation: Report of 76cases

VernacularTitle:乳腺癌新辅助化疗的非随机临床观察:附76例报告
Author: Dehai XIONG ; Shide LIU ; Yi LIU
Publication Type:Journal Article
Keywords: Breast cancer; Neoadjuvant chemotherapy; Anthracycline
From: Journal of Endocrine Surgery 2009;3(2):110-112
CountryChina
Language:Chinese
Abstract: Objective To investigate the breast cancer neoadjuvant chemotherapy for clinical applica-tion.Methods Given suitable breast cancer patients anthracycline-based combination chemotherapy, 2 ～ 4 cy-cle after the surgery were observed to assess their clinical efficacy and conform to conditions and are compatible with the same period did not receive neoadjuvant chemotherapy for a comparative analysis of cases.Results Ac-ceptance of neoadjuvant chemotherapy group of cases the total effective rate was 89.47%, 1-year and 3-year over-all survival rate significantly improved, 17 cases due to neoadjuvant chemotherapy benefit received axillary lymph node dissection to narrow the scope of the modified radical mastectomy for breast cancer, five cases of implemen-tation of the breast retain on the radical operation of breast cancer.Conclusions Neoadjuvant chemotherapy can effectively reduce the clinical stage of breast cancer, some patients benefit from breast-implementation, such as radical mastectomy or surgery to narrow the scope, postoperative survival and prognosis of breast cancer is there-fore improved.