Ectopic pituitary adenoma in clivus: 2 cases report and review of the literature
10.3760/cma.j.issn.1674-6090.2010.04.005
- VernacularTitle:斜坡异位垂体腺瘤2例并文献复习
- Author:
Bin LIU
;
Yong WANG
- Publication Type:Journal Article
- Keywords:
Ectopic pituitary adenoma;
Clivus
- From:
Journal of Endocrine Surgery
2010;04(4):228-230
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore clinical and neuroimagine features, as well as the management of rare ectopic pituitary adenoma in clivus. Methods We reported two cases of ectopic pituitary adenoma verified by histology in the clivus region, reviewed the relevant literature briefly, summarized the clinical and neuroimaging features, along with the management of ectopic pituitary adenoma in clivus. Results Ectopic pituitary adenoma in clivus caused symptoms of endocrinopathy and/or neurological dysfunction. Imaging studies showed an occupying lesion in the clivus. Pituitary adenoma was diagnosed in one patient preoperatively, the other was diagnosed as chordoma. The tumors were microsurgically removed through the trans-sphenoidal route. Tumor was radically removed in one patient, and during one-year follow-up, there was no recurrence. The other was partially resected, and suffered postoperative cerebrospinal fluid rhinorrhea and intracranial infection, follow-up of this patient lost finally. Conclusions The patients with ectopic pituitary adenoma in clivus have endocrinopathy or/and neurological dysfunction, and MRI plays a valuable role in the diagnosis. Although extremly rare, ectopic pituitary tumour needs to be considered in case of an occupying lesion in the clivus. Radical resection of tumor can cure the patient.
