Therapeutic efficacy comparation between transcather arterial chemoembolization and comprehensive therapy in 216 patients with primary advanced hepatocellular carcinoma

VernacularTitle:216例中晚期原发性肝细胞癌介入化疗及综合治疗的疗效比较
Author: Xiao HU ; Chengzhong WU
Publication Type:Journal Article
Keywords: Primary hepatocellular carcinoma; Transcather arterial chemoembolization; Intraperito-neal perfusion chemotherapy
From: Journal of Endocrine Surgery 2009;3(2):103-106
CountryChina
Language:Chinese
Abstract: Objective To compare the therapeutic efficacy and adverse effects between transcather arte-rial chemoembolization(TACE) and comprehensive therapy in primary advanced heptocellular carcinoma(HCC).Methods 216 patients with primary HCC were arranged randomly into two groups:104 (group A) were treated with TACE alone,the rest(group B)were treated with TACE combined with intraperitoneal perfusion chemothera-py, Chinese herbs and immunotherapy.The therapeutic efficacy and adverse effects were analysed and compared between two groups.Results The CR + PR rates were 28.84% in group A and 34.82% in group B.The 4-year survival rates were 1.92% in group A and 3.87% in group B(P < 0.05).There were no severe side effects in both groups.Conclusions The short-term effective rate and 4-year survival rate in comprehensive treatment group were superior to the control group.Therefore, the comprehensive treatment is worthwhile to use in primary advanced hepatocellular carcinoma.