Minimal access parathyroidectomy for primary hyperparathyroidism caused by parathyroid adenoma:report of 28 cases

VernacularTitle:甲状旁腺腺瘤致原发性甲状旁腺功能亢进症的小切口手术治疗(附28例临床分析)
Author: Meiping SHEN ; Min YANG ; Zhengyan WU
Publication Type:Journal Article
Keywords: Primary hyperparathyroidism(PHPT); Surgical treatment; Minimal access surgery
From: Journal of Endocrine Surgery 2009;3(3):172-174
CountryChina
Language:Chinese
Abstract: Objective To evaluate our experience of minimal access parathyroidectomy for primary hy-perparathyroidism (PHPT) caused by parathyroid adenoma. Methods From Jan 2000 to Jan 2009, clinical data of 28 cases of PHPT treated by minimal access surgery were analyzed retrospectively. Results All patients except 3 had severe clinical manifestations, serum calcium and parathyroid hormonal (PTH) of all the cases were elevat-ed. The rate of accuracy of preoperation localization by the sestamibi scan combined with ultrasound was 100%.The pathological diagnoses of all the 28 cases were uni-gland parathyroid adenoma. Within the follow-up of 6 months, no case suffered complication and recurrence, the levels of serum calcium were normal or decreased slightly, and the levels of PTH were normal or elevated slightly but no higher than 2 times of normal PTH level. Conclusions Preoperative localization is very helpful by using combination of sestamibi and ultrasound scan. Minimally invasive parathyroidectomy is a kind of improving procedure for the localized parathyroid adenoma.