Expression of CD1a＋ DC in fair follicle of human normal skin and psoriasis
10.3321/j.issn:1007-8738.2001.01.015
- VernacularTitle:正常人与寻常型银屑病患者毛囊 CD1a＋树突状细胞的表达
- Author:
Qing XIA
;
Xuejun ZHANG
- Publication Type:Journal Article
- From:
Journal of Cellular and Molecular Immunology
2001;17(1):50-51
- CountryChina
- Language:Chinese
-
Abstract:
Aim To explore the expression of CD1a＋ DC in fair follicle of normal human skin and psoriasis patients. Methods Expressions of CD1a＋ DC in 10 fair follicles of psoriasis patients and skins of 8 normal human were detected by SABC immunohistochemical staining. Results The numbers of CD1a＋ DC in upper limb skin and scalps's fair follicle were 13 and 15 respectively. The number of CD1a＋ DC in fair follicle of psoriasis patients was 16,slightly more than that in skins. There was obviously higher density of CD1a＋ DC in psoriasis fair follicle and its number was 46± 15/mm2. Conclusion The area of fair follicle is connected with the start and redistribution of CD1a＋ DC,and the fair follicle may have important effect on development of vulgaris psoriasis.
