Expression and clinical meaning of nm23-H1 gene in gastric carcinoma tissue
10.3760/cma.j.issn.1674-6090.2009.02.006
- VernacularTitle:nm23-H1基因在胃癌中表达及临床意义
- Author:
Kai LU
;
Zhuangkai YAO
;
Yanwen LIU
;
Cheng ZHAO
;
Yongping LIU
- Publication Type:Journal Article
- Keywords:
Gastric carcinoma;
nm23-H1;
Immunohistochemistry
- From:
Journal of Endocrine Surgery
2009;3(2):88-90
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relationship of expression of metastasis suppressor gene nin23-H1 protein in gastric carcinoma tissue and tumor infiltration and metastasis.Methods The expression of metastasis suppressor gene nm23-H1 protein in 50 gastric carcinoma tissues was detected by SP immunohistocbemistry tech-nology.Results Correlations were presented among expression of nm23-H1 protein, infiltrate grade of gastric carcinoma, lymph node metastasis and TNM stage.Conclusions Expression of nm23-H1 may suppress infiltra-tion and metastasis of gastric carcinoma, Low expression of nm23-H1 protein may be of great reference value in judgement of tumor progression, metastasis and reeidivation.
