Analysis of two intensive therapies in type 2 diabetes mellitus
10.3760/cma.j.issn.1674-6090.2011.01.018
- VernacularTitle:两种强化降糖方案治疗2型糖尿病的临床分析
- Author:
Yin WU
;
Min WU
;
Qiu XU
;
Shengbing LI
- Publication Type:Journal Article
- Keywords:
Continuous subcutaneous insulin infusion(CSⅡ);
Multiple subcutaneous insulin infusion (MSⅡ);
Type 2 diabetes mellitus;
Intensive therapy
- From:
Journal of Endocrine Surgery
2011;05(1):55-56
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare efficacy of two intensive therapies:continuous subcutaneous insulin infusion(CSⅡ) and multiple subcutaneous insulin infusion (MSⅡ) for treatment of type 2 diabetes mellitus.Methods 60 patients with type 2 diabetes mellitus were randomly divided into 2 groups. Patients in CSⅡ group were treated by insulin (Novolin R) through a infusion pump. Patients in MSⅡ group were treated by Novolin R before meals (3 times a day) and Novolin N at bedtime. Blood glucose was monitored the whole day before and after treatment. Time required for blood glucose to reach the standard level, insulin dosage and hypoglycemia incidence were compared between the 2 groups before and after treatment. Results Both of the 2 therapeutic methods effectively controlled blood glucose (P＜0.05). However, the 2 groups had significant difference in terms of the time required for blood glucose to reach the standard level ( 3.6 ± 1.2 d vs. 9.4 ± 3.2 d, P ＜ 0. 01 ), daily insulin consumption (35.2 ± 8.5 u vs. 43.2 ± 10. 1 u, P ＜0. 01 ) and hypoglycemia incidence (2. 1% vs.9.7%, P ＜0.01 ). Conclusions CSⅡ and MSⅡ are effective for treatment of type 2 diabetes mellitus. CSⅡ is superior to MSⅡ due to its advantages of quick response, safety, and less insulin consumption.
