Immune suppression induced by auto-keratinoc-ytes in intermingled skin grafting
10.3321/j.issn:1007-8738.2001.04.015
- VernacularTitle:自体角质形成细胞在混合皮肤移植中诱导免疫抑制
- Author:
Hong ZHOU
;
Baihua SHEN
;
Ningli LI
;
Zexian ZHEN
;
Guangyan ZHOU
- Publication Type:Journal Article
- From:
Journal of Cellular and Molecular Immunology
2001;17(4):346-347
- CountryChina
- Language:Chinese
-
Abstract:
Aim To explore the mechanism of the immune tolerance induced by the auto-islets in the intermingled skin grafting. Methods The mixed epidermal cell and lymphocyte culture (MELC) was established, in which auto-keratinocytes were added to mimic the effect exerted by the auto-islets in vivo. Results Auto-keratinocytes could inhibit the lympho-proliferation induced by alloantigen. Conclusion The immune tolerance induced by auto-islets may be related to the function of auto-keratinocytes as antigen presenting cells.
