Efficacy of weight loss training and oral intake of metformin in obese women with polycystic ovary syndrome
10.3760/cma.j.issn.1674-6090.2014.03.006
- VernacularTitle:减重训练及口服二甲双胍对肥胖型多囊卵巢综合征的疗效
- Author:
Jing YUAN
- Publication Type:Journal Article
- Keywords:
Weight loss training;
Metformin;
Obese women with polycystic ovary syndrome
- From:
Journal of Endocrine Surgery
2014;8(3):197-199
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the clinical effect of weight loss training and oral intake of mefformin on obese women with polycystic ovary syndrome.Methods 60 cases of obese women with polycystic ovary syndrome in Nan'an District Maternal and Child Health Hospital were studied.They were divided into 2 groups,30 cases in each group.The control group received simple weight loss training and the observation group received weight loss training combined with the oral administration of metformin.The clinical data of the 60 cases were retrospectively analyzed and the clinical efficacy and safety of different treatment methods were evaluated.Results After treatment,two groups of patients have been effectively improved.16 cases(53.3％)in the control group and 29 cases(96.7％)in the observation group resumed normal menstruation,and the differences had statistical significance.Fasting blood sugar(FBS),BMI,testosterone and luteinizing hormone levels of the two groups had significant improvement after treatment,in addition,the improvement of these indicator were more obvious in the observation group than those in the control group,and the difference had statistical significance.The difference of FBS,BMI,testosterone and luteinizing hormone levels had statistical significance between before and after treatment(P =0.003 7,0.001 2,0.002 0 and 0.002 4,respectively).Conclusion The combination therapy of weight loss training and oral intake of metformin is effective in treating obese women with polycystic ovary syndrome.It is the main method in treating obese women with polycystic ovary syndrome.
