The significance of serum parathyroid hormone level on the first day after total thyroidectomy
10.3760/cma.j.issn.1674-6090.2014.01.005
- VernacularTitle:甲状腺全切术后第一天甲状旁腺激素测定的临床意义
- Author:
Chuang CHEN
;
Bin ZHAO
;
Wei DING
;
Zhihao NIU
;
Hong ZHANG
- Publication Type:Journal Article
- Keywords:
Total thyroidectomy;
Parathyroid hormone;
Serum calcium;
Hypocalcemia
- From:
Journal of Endocrine Surgery
2014;8(1):15-17
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determinate whether the first post-operative day serum parathyroid hormone (PTH) is more effective than serum calcium in predicting hypocalcemia after total thyroidectomy.Methods According to PTH level on the first post-operative day,104 patients after total thyroidectomy were divided into different groups.Patient's serum calcium was measured,the number of patients who developed hypocalcemia and the time for calcium supplement were recored.Results Serum PTH was more accurate in predicting hypocalcemia than serum calcium.There were 26 patients whose PTH value was ＜ 5 pg/ml,among whom 7 patients had transient hypocalcemia and symptoms,while 5 of them developed hypocalcemia for long time and needed long-term calcium supplement.The positive predictive value of group PTH value ＜ 5 pg/ml was 28％,and the accurate rate was 46％,higher than other groups.Besides,the positive predictive value and the accurate rate of PTH value ＜ 5 pg/ml was higher than serum calcium.Conclusion Serum PTH is more effective in determining hypocalcemia after total thyroidectomy than serum calcium,and PTH value ＜ 5 pg/ml on the first post-operative day is a reliable marker in predicting hypocalcemia after total thyroidectomy.
