Effect of lipid changes during pregnancy on pregnancy induced hypertension syndrome
10.3760/cma.j.issn.1674-6090.2015.02.020
- VernacularTitle:妊娠期血脂变化对妊娠高血压综合征的影响
- Author:
Jun CHEN
- Publication Type:Journal Article
- Keywords:
Pregnancy;
Blood lipid;
Pregnancy induced hypertension syndrome
- From:
Journal of Endocrine Surgery
2015;(2):164-166
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation between changes of blood lipid in pregnant women and pregnancy induced hypertension syndrome ( PIHS) .Methods 103 cases with PIHS admitted from Sep .2010 to Sep.2013 were the PIHS group, 100 cases of pregnant women without hypertension were the control group , and 100 cases of non-pregnant women were the normal group .The blood lipids of each group were detected .Re-sults Total cholesterol(TC), triglyceride(TG), low density lipoprotein cholesterol (LDL-C), apolipoprotein b (ApoB)and lipoprotein-a[LP(a)]were significantly lower while high-density lipoprotein cholesterol(HDL-C)and apolipoprotein a1( ApoAI) were significantly higher in patients with mild PIHS than in patients with severe PIHS (P<0.05).TC, TG, LDL-C, ApoB, and LP(a)were significantly higher in PIHS group than in the normal group and the control group(P<0.05).HDL-C and ApoAI levels in PIHS group were significantly higher than those in the normal group, but lower than those in the control group (P<0.05).In addition, normal blood lipid indexes were significantly higher in the control group than in the normal group ( P<0.05 ) .Conclusion We should pay more attention to HDL-C and ApoAI in order to accomplish the goal of early discovery and early treat-ment of PIHS, improving maternal and neonatal outcomes .