Effects of laparoscopic gastric bypass surgery on lipid metabolism in obese patients
10.3760/cma.j.issn.1674-6090.2014.06.009
- VernacularTitle:腹腔镜胃旁路术对肥胖患者脂质代谢的影响
- Author:
Huan LIU
;
Hui LIANG
;
Wei GUAN
;
Qing CAO
- Publication Type:Journal Article
- Keywords:
Obesity;
Lipid metabolism;
Bariatric surgery;
Gastric bypass;
Laparoscopy
- From:
Journal of Endocrine Surgery
2014;(6):469-471
- CountryChina
- Language:Chinese
-
Abstract:
Objective To assess the lipid profiles of obese patients undergoing laparoscopic gastric by-pass surgery.Methods A retrospective observational study was performed , involving 25 patients(BMI>28 kg/m2 ) who consecutively underwent gastric bypass surgery in the First Affiliated Hospital of Nanjing Medical Univer -sity from Oct.2010 to Dec.2012.For the surgery, a small gastric pouch about 30 ml was performed with 100 cm biliopancreatic limb and 100-200 cm alimentary limb.Total cholesterol(TC),triglycerides(TG),high density lip-oprotein( HDL) and low density lipoprotein ( LDL) at baseline and 1, 3, 6, 9 and 12 months after surgery were measured.Related complications were recorded .Results All surgeries were performed laparoscopically and no serious complications occurred .TC, TG, and LDL significantly reduced after the surgery (P<0.05 for all).In-versely, HDL disclosed a significant rise(P<0.05).Of the lipid profiles at baseline, only HDL concentration displayed a correlation with BMI .Percentage of excess weight loss ( PEWL ) displayed significant correlation with the variety of TG、LDL、HDL after surgery(P<0.05 for all).Conclusions Laparoscopic gastric bypass is a safe operation which improves the lipid metabolism of obese patients .The operation can decrease the concentration of TC, TG, LDL and increase HDL level .
