Blood cell and electrolyte change in diagnosis and surgical treatment of Cushing's disease
10.3760/cma.j.issn.1674-6090.2011.05.013
- VernacularTitle:探讨血细胞、电解质在库欣病的诊断和手术疗效中的价值
- Author:
Xiuhua SHI
;
Changyan FAN
;
Qingfang SUN
;
Liuguan BIAN
;
Weiguo ZHAO
;
Fukang SUN
;
Weiqing WANG
;
Guang NING
- Publication Type:Journal Article
- Keywords:
Cushing's disease;
Blood cell;
Electrolyte
- From:
Journal of Endocrine Surgery
2011;05(5):323-326
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the diagnostic significance of blood cells and electrolyte in preoperative diagnosis and surgical treatment of Cushing's disease (CD).Methods 116 csses of CD and 21 cases of adrenocortical adenoma (ACA) patients pathologically proven adrenocorticotropic hormone (ACTH) adenoma from Jan.2003 to Dec.2010 were enrolled into the study.They were given transsphenoidal surgery (TSS) and laparoscopic resection of adrenal adenoma (LRAA).Patients were divided into remission group ( group A),non-remission group (group B) and ACA group (group C) according to the remission criteria of CD.The preoperative and postoperative level of blood cells and electrolyte were determined.Results TSS treatment improved the abnormal level of blood cells and electrolyte in patients with CD.Group A had significant change in preoperative and postoperative level of blood cells and electrolyte,while group B and group C didn't.Conclusions Compared with the endocrine examination items which need huge expense and harsh conditions,the change of blood cells and electrolyte level is more superior in assessing diagnostic and cruative effects on CD patients.
