Endoscopic Resection as a Possible Radical Treatment for Duodenal Gangliocytic Paraganglioma: A Report of Four Cases.
10.4166/kjg.2014.63.2.114
- Author:
Se Jeong PARK
1
;
Do Hoon KIM
;
Hyun LIM
;
Jeong Hoon LEE
;
Kee Don CHOI
;
Ho June SONG
;
Gin Hyug LEE
;
Hwoon Yong JUNG
;
Jin Ho KIM
;
Ji Young PARK
Author Information
1. Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. dohoon.md@gmail.com
- Publication Type:Case Reports
- Keywords:
Paraganglioma;
Duodenum
- MeSH:
Aged;
Ampulla of Vater/pathology;
Chromogranin A/metabolism;
Colonoscopy;
Duodenal Neoplasms/pathology/*surgery;
Endoscopy, Gastrointestinal;
Female;
Humans;
Immunohistochemistry;
Intestinal Mucosa/pathology/surgery;
Male;
Middle Aged;
Neuroendocrine Tumors/pathology/surgery;
Paraganglioma/pathology/*surgery;
S100 Proteins/metabolism;
Synaptophysin/metabolism;
Tomography, X-Ray Computed
- From:The Korean Journal of Gastroenterology
2014;63(2):114-119
- CountryRepublic of Korea
- Language:English
-
Abstract:
Gangliocytic paraganglioma (GP) is a rare, benign tumor which is usually found in the duodenum. We here report four recent cases of GP, with successful endoscopic resection in three cases, including a lesion on the ampulla of Vater. In all cases, each lesion had a stalk that facilitated removal using an endoscopic approach. Endoscopic mucosal resection is a feasible and safe treatment if the location, depth, and lymph node status are all favorable and is also helpful for definite diagnosis of unknown duodenal mass. To avoid morbidity resulting from open surgical resection, careful inspection for the peduncle of the GP will help determine the feasibility of endoscopic resection.