Clinicopathologic features and treatment of pure mucinous breast carcinoma
10.3760/cma.j.issn.1674-6090.2011.02.014
- VernacularTitle:单纯乳腺粘液癌的临床病理特点及治疗
- Author:
Meng YANG
;
Xin LI
;
Chunhong PANG
;
Linping HUANG
- Publication Type:Journal Article
- Keywords:
Pure mucinous breast carcinoma;
Pathology;
Treatment;
Prognosis
- From:
Journal of Endocrine Surgery
2011;05(2):114-116
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore clinical characteristics,pathology,prognosis and proper treatment of pure mucinous breast carcinoma(PMBC).Methods Retrospective analysis Was carried out on patients with PMBC who were admitted from Jan.2004 to Dec.2010.Results PMBC patients accounted for 2.6%of all the patients with breast cancer treated at the same period.The mean age of PMBC patients was(55.28±15.73)years,ranging from 32 years to 81 years.The tumor diameter was from 1 to 10 cm and axillary lymph node involvement was 0%.Immunohistochemieal detection showed the positive rate of estrogen receptor(ER),progesterone receptor(PR),HER-2 and p53 was 96%,92%,0%and 32%respectively.All patients underwent operation and polychemotherapy(cyclophosphamide+Adriamycin,Paclitaxel+Adriamyein).12 cases received tamoxifen,13 cases received letrozole and 8 cases received postoperative irradiation.All the patients were followed up from 1 month to 6 years and the overall survival rate was 100%.Conclusions PMBC is a favorable histological type of breast carcinoma with good prognosis.Proper surgical and adjuvant therapy is important to improve survival rate and life quality.Molecular biologic parameters should be given enough consideration into prognosis evaluation.
