THE INVESTIGATION OF DIFFERENT POPULATION'S TRANSFUSION-TRANSMITTED VIRUS-DNA IN SHAANXI PROVINCE
- Author:
Shuangsuo DANG
;
Yanan CHENG
;
Rong ZENG
;
Xunming CHENG
- Publication Type:Journal Article
- Keywords:
transfusion transmitted virus(TTV);
polymerase chain reaction(PCR);
non-A~non-G hepatitis
- From:
Journal of Pharmaceutical Analysis
2000;12(2):129-131
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate transfusion transmitted virus (TTV) infection among population of different groups in Shaanxi Province. Methods A nested polymerase chain reaction (PCR) with primers from ORF1 of TTV genome was established to detect TTV-DNA in serum of the patients. ResultsTTV-DAN was detected in the sera of 3 of 50 cases of general population(6%), 2 of 30 cases of vocational blood donors(6.7%),21 of 97 cases with Type B hepatitis (21. 6%), 9 of 35 cases of Type C hepatitis (25. 7%),and 23 of 40 cases with non-A~ non-G hepatitis (57.5 % ). ConclusionThere is TTV infection among general population in Shaanxi Province. TTV may be an impor- tant agent to cause non-A~non-G hepatitis. And the patients with HBV or HCV can have overlapping TTV infection.