INVESTIGATION ON RELATIONSHIP BETWEEN PREOPERATIONALSENSITIZATION AND CROSSMATCH
- Author:
Bin WANG
;
Yiguo FENG
;
Wujun XUE
;
Puxun TIAN
- Publication Type:Journal Article
- From:
Journal of Pharmaceutical Analysis
2001;13(1):86-88
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between HLA sensitization and crossmatch and to assess its clinical value. Methods The subjects were divided into 3 groups :high sensitization group (PRA≥40%),low sensitization group (40%>PRA≥10%) and non-sensitization group (PRA<10%) according to the HLA antibody level detected by ELISA. The results of crossmatch were compared among the 3 groups. Results There was significant difference among the ratio of positive crossmatch in high sensitization group (39.4%),low sensitization group (10.5%)and non-sensitization group (2. 6%). Conclusion The sensitization level is positively correlated with the result of crossmatch. The improvement of matching precision can be made by using both of techniques mentioned above.