A Case of Extensive Cutaneous Metastasis from Squamous Cell Carcinoma of the Uterine Cervix.
- Author:
Hyunju JIN
1
;
Won Jeong KIM
;
Je Ho MUN
;
Margaret SONG
;
Hoon Soo KIM
;
Hyun Chang KO
;
Moon Bum KIM
;
Byung Soo KIM
Author Information
1. Department of Dermatology, School of Medicine, Pusan National University, Busan, Korea. dockbs@pusan.ac.kr
- Publication Type:Case Report
- Keywords:
Cutaneous metastasis;
Squamous cell carcinoma;
Uterine cervical cancer
- MeSH:
Abdominal Wall;
Carcinoma, Squamous Cell*;
Cervix Uteri*;
Dermis;
Epidermis;
Female;
Humans;
Incidence;
Keratin-7;
Keratins;
Korea;
Liver;
Lower Extremity;
Lung;
Middle Aged;
Neoplasm Metastasis*;
Thoracic Wall;
Ulcer;
Upper Extremity;
Uterine Cervical Neoplasms;
Vulva
- From:Korean Journal of Dermatology
2014;52(2):115-119
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Carcinoma of the uterine cervix is a common malignancy for women in Korea. It frequently metastasizes to the lungs, bone, or liver, but cutaneous metastasis is rare, with a reported incidence of only 1.3%. In cases of cutaneous metastasis, the lesions present in the forms of nodules, ulcers, or plaques, and are generally located in the abdominal wall, vulva, anterior chest wall, lower extremities, and upper extremities. Here, we describe a case of a 64-year-old woman diagnosed with cutaneous metastases from squamous cell carcinoma of the uterine cervix on both flanks, lower abdominal wall, and both inguinal areas, three years after receiving chemoradiation therapy. At presentation, the primary carcinoma had been resolved completely. Histological and immunohistochemical findings revealed intact epidermis and infiltration of tumor cells in the dermis, which showed positivity for cytokeratin 5/6, cytokeratin 7, and tumor protein 63, consistent with metastatic squamous cell carcinoma of the uterine cervix.
