ROLE OF PERIPHERAL LYMPHOCYTES SIALYL LEWIS(X) (CD15s)ANTIGEN BEFORE AND AFTER KIDNEY TRANSPLANTATION
- Author:
Xiaoming PAN
;
Yong WANG
;
Wujun XUE
;
Puxun TIAN
- Publication Type:Journal Article
- Keywords:
renal transplantation;
CD15s;
immunosuppression
- From:
Journal of Pharmaceutical Analysis
2006;18(2):187-190
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the role of peripheral lymphocytes Sialyl Lewis(x) (CD15s) antigen before and after kidney transplantation. Methods Flow cytometry technique was applied to examine the expression of peripheral lymphoid cell surface CD15s antigen after renal transplantation, and to evaluate various therapeutic regimen. Results The statistic analysis results of peripheral lymphoid cell surface CD15s antigen expression level showed that there was significant difference among the patients with acute rejection, long-term dialysis and with normal renal function post-transplant; significant difference of CD15s expression level between group of rejection and infection; no significant difference of CD15s expression among the different groups treated by various therapeutic regimens. Conclusion The different therapeutic regimen has no influence to CD15s expression; Detection of peripheral lymphoid cell surface CD15s antigen expression periodically, intelligently make convenience to understand suitable status of immunosuppression.
