Effects of labor analgesia on maternal and neonatal outcome by epidural low concentration of bupivacaine combined with anisodamine
- Author:
Xiaoli YANG
;
Chunqin ZHOU
;
Xiaogang LI
;
Xiaodong SHEN
;
Yuliang ZOU
- Publication Type:Journal Article
- Keywords:
epidural block;
anisodamine;
bupivacaine;
labor analgesia
- From:
Journal of Pharmaceutical Analysis
2008;20(4):278-281
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effects of labor analgesia on maternal and neonatal outcome by epidural application of 0.125% bupivacaine combined with anisodamine on the labor stage, and modes of delivery and neonatal Apgar's score. Methods A total of 220 primiparaes with full-term pregnancy, monocyesis and fetal head presentation without any obstetrical or systematic complications were chosen and divided into analgesic group and control group (110 in each group). The mixture of bupivaeaine and anisodamine was injected into the epidural space of the parturients in the analgesic group while those patients in the control group did not receive any analgesics. Results The analgesic effect was satisfactory (91.8 %), and no side effects occurred in the second stage of labor. The instrument delivery rate was lower in the analgesic group, and there was no significant difference between the two groups in neonatal Apgar's score. Conclusion The method is feasible in clinic for labor pain relief without increasing the rate of dystocla and complications of delivery.
