Clinical manifestations and cerebral angiographic findings of moyamoya disease
- Author:
Jianfeng HAN
;
Chengtai WANG
;
Jianbo YANG
;
Feng GUO
;
Zhengyi LI
- Publication Type:Journal Article
- Keywords:
moyamoya disease;
digital subtraction angiography;
clinical characteristic
- From:
Journal of Pharmaceutical Analysis
2010;22(2):131-134
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical features and angiographic findings of moyamoya disease (MMD) as well as their relationship. Methods A total of 22 MMD patients received routine digital substraction angiography (DSA). The clinical manifestations and angiographic findings were analyzed. Results Clinical manifestations varied and each patient often had multiple symptoms, including cerebral infarction in 9 patients with an average age of 23.6 (13-39 years) and cerebral hemorrhage in 7 patients with an average age of 31.2 (28-46 years). Angiographic examination found that all the diseased sides showed MMD blood vessels. The patients who received encephalo-myo-arterio-synangiosis (EMAS) had better prognosis than those without receiving the treatment. Conclusion Cerebral infarction is frequent in children and adolescents with MMD, whereas cerebral hemorrhage is common in adults. DSA is a golden criterion for diagnosing MMD. Surgical treatment, EMAS blood supply reconstruction in particular, should be prescribed.