Effect of psychological intervention combined with clopidogrel and Aspirin Enteric-coated Tablets on angina pectoris of coronary heart disease
10.3969/j.issn.1005-1678.2017.08.063
- VernacularTitle:心理干预联合氯吡格雷、阿司匹林肠溶片对冠心病心绞痛疗效观察
- Author:
Qun XU
;
Yaqin SHEN
- Keywords:
psychological intervention;
clopidogrel;
aspirin tablet;
coronary heart disease (CHD);
angina pectoris
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(8):156-157,160
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of combination therapy (psychological intervention+clopidogrel+aspirin) for coronary heart disease. Methods 88 cases were selected from January 2016 to April 2017 in patients with coronary heart disease in our hospital. In a randomized approach, patients were divided into treatment groups and control groups, with 44 cases per patient. Patients in the control group were treated with aspirin, and the treatment group was treated with a combination therapy (psychological intervention+clopidogrel+aspirin). The treatment effect, angina and adverse reaction were observed and compared. Results Comparing the therapeutic effect of two groups of patients, the treatment group total effective rate was 97.73%, control group total effective rate was 79.55%, significant difference was statistically significant (P<0.05); Compared two groups of patients with angina, the treatment group patients with onset time (4.32±1.18) shorter, longer time interval (5.03 ±1.34), less number of attacks (1.67±0.49), with statistical significance (P<0.05); Compared to the adverse reactions in the two groups, the incidence of adverse reactions in the treatment group was 4.55%, compared with 18.18% in the control group. Statistical significance (P<0.05). Conclusion Psychological intervention in combination with clopidogrel and aspirin enteric-coated metformin hydrochloride in the treatment, in the clinical treatment of patients with coronary heart disease angina pectoris, shows good therapeutic effect, has higher application value.