Effect of continuous positive airway pressure on glycosylated hemoglobin levels in patients with obstructive sleep apnea syndrome
10.3969/j.issn.1005-1678.2017.08.181
- VernacularTitle:持续气道正压通气对阻塞性睡眠呼吸暂停综合征患者糖化血红蛋白水平的影响
- Author:
Tao SUN
;
Xiaojing LIU
;
Quan LI
;
Xuebin WANG
- Keywords:
Obstructive sleep apnea-hypopnea syndrome (OSAHS);
hemoglobin Alc (Hba1c);
continuous positive airway pressure (CPAP)
- From:
Chinese Journal of Biochemical Pharmaceutics
2017;37(8):423-424,426
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of obstructive sleep apnea syndrome (OSAHS) patients with glycosylated hemoglobin (HbA1c) levels, assessment of continuous positive airway pressure (CPAP) effect on the level of HbA1c in patients with OSAHS. Methods From January 2013 to December 2016, eighty patients with OSAHS were divided into mild group, eighteen cases, moderate group twenty cases, severe group forty-two cases according to the apnea hypopnea index (AHI). Thirty healthy subjects were chosen as the control group. All the treatment groups were treated with CPAP for three months. Overnight polysomnography and HbA1c test were performed before and after treatment, and the control group was examined by HbA1c before treatment. Results The level of glycosylated hemoglobin in the middle and severe group was higher than that of the control group(P<0.05). After treatment, the glycated hemoglobin levels in the moderate and severe groups were significantly lower(P<0.05), and the sleep apnea hypopnea index, the lowest SaO2 and the average SaO2 level were significantly improved(P<0.01). Conclusion Glycated hemoglobin levels increased significantly in patients with moderate and severe OSAHS, and decreased HbA1c levels in patients with moderate and severe OSAHS after CPAP treatment.
