Localization diagnosis and surgical treatment of intractable occipital epilepsy
10.11659/jjssx.11E016065
- VernacularTitle:难治性枕叶癫痫的定位诊断和手术治疗研究
- Author:
Qiao LIN
;
Pengfan YANG
;
Zhen MEI
;
Huijian ZHANG
;
Jiasheng PEI
;
Jianwu WU
;
Shousen WANG
- Keywords:
occipital lobe epilepsy;
diagnostic modalities;
surgery;
visual field deficits;
seizure
- From:
Journal of Regional Anatomy and Operative Surgery
2017;26(8):597-601
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the preoperative localization diagnosis and surgical techniques of intractable occipital lobe epilepsy.Methods Retrospectively studied 37 patients diagnosed as occipital lobe epilepsy and underwent focal occipital resections for epilepsy.The semiology,scalp electroencephalography,MRI,fluorodeoxyglucose-positron emission tomography(FDG-PET),and intracranial EEG monitoring were used to localize the epileptogenic zones.The long-term seizure outcomes were assessed according to the Engel classification scheme.Results Visual symptoms were present in 25 patients preoperatively in this series.MRI displayed occipital lobe lesions in 15 patients,and FDG-PET revealed hypometabolism in or adjacent to epileptogenic zones.And 30 patients' epileptogenic zones and functional areas were defined by intracranial EEG monitoring.Visual field deficits were present in 35.3% of patients preoperatively,and 61% had new or aggravated visual field deficits after surgery.After a mean follow-up of 41 months,81.1% of the patients were seizure free or rarely had seizures.Conclusion The curative effect of the surgery on the medically intractable occipital lobe epilepsy is good.Intracranial EEG monitoring with electrodes extensively covering the occipital lobe and adjacent areas can be useful to demarcate the epileptogenic zones and the visural cortex,and it may prevent aggravation of the visual field deficits as much as possible.
