Application of PET probes in Alzheimer's disease
10.7644/j.issn.1674-9960.2017.04.017
- VernacularTitle:PET分子探针在阿尔茨海默病中的应用
- Author:
Qi LIU
;
Yuan GAO
- Keywords:
Alzheimer's disease;
brain imaging;
positron emission tomography;
molecular probes;
Aβ;
Tau
- From:
Military Medical Sciences
2017;41(4):318-321
- CountryChina
- Language:Chinese
-
Abstract:
Alzheimer's disease (AD) is the most common type of dementi a.PET probes can specifically detect the in vivo amyloid β peptide(Aβ) and Tau protein in AD inpatients' brain.The application of PET probes in AD is important for its early diagnosis and early intervention.US FDA has approved three PET probes for Aβ imaging while probes for Tau are still under research and development.This review summarizes current development of Aβ and Tau PET probes used for AD.