Mucosal microvascular morphological changes in superifcial nasopharyngeal carcinoma and its clinical value under narrow band imaging
10.3969/j.issn.1007-1989.2016.12.010
- VernacularTitle:窄带成像技术下浅表型鼻咽癌黏膜表面微血管形态特点及临床价值
- Author:
Lining WEI
;
Hao CHEN
- Keywords:
narrow band imaging,NBI;
endoscopy;
superficial nasopharyngeal carcinoma;
microvascular morphological characteristics
- From:
China Journal of Endoscopy
2016;22(12):49-54
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the mucosal microvascular morphological changes in superficial nasopharyngeal carcinoma (NPC) and its clinical value under narrow band imaging (NBI).Methods From 2015.01 to 2016.01, 182 patients at high risk for NPC received biopsy of superficial nasopharyngeal lesions due to the existence of irregular vessel under NBI while they were examined with electronic nasopharyngolaryngoscope quipped with white light mode and NBI mode. Compared the mucosal microvascular morphological characteristics of different diseases based on pathological result and evaluated the diagnostic efifcacy of NBI.Result Under NBI, the mucosal microvascular morphological characteristics of nasopharyngeal carcinoma under NBI mode were of that concentrated brown spots (CBS, 38.24 %) and irregularly dilated branching vessels (IDBV, 41.18 %) with demarcation line (DL, 52.94 %). In addition, IDBV were the main microvascular pattern in fresh NPC cases (57.89 %,P = 0.000), while CBS were the main microvascular pattern in post-radiation local recurrent NPC cases (60.00 %,P = 0.000). The sensitivity, speciifcity, positive predictive value, negative predictive values and diagnostic coincidence rate of NBI in NPC screening were 79.41 %, 95.95 %, 81.82 %, 95.30 % and 92.86 %, respectively.Conclusion NBI endoscopy is a promising tool for improving the early diagnosis of NPC by detecting mucosal microvascular morphological changes in superifcial NPC.
