Factors of postoperative intracranial infection after endoscopic repair of cerebrospinal fluid rhinorrhea
10.3969/j.issn.1007-1989.2016.06.014
- VernacularTitle:内镜下脑脊液鼻漏修补术后颅内感染的影响因素
- Author:
Tingting CHEN
;
Jin ZHAO
;
Fanghui LIU
- Keywords:
nasal endoscope;
cerebrospinal fluid rhinorrhea repair;
intracranial infection
- From:
China Journal of Endoscopy
2016;22(6):52-55
- CountryChina
- Language:Chinese
-
Abstract:
Objectives To investigate risk factors for postoperative intracranial infection after nasal endoscopic re-pair of cerebrospinal fluid rhinorrhea, in order to provide a reference for later treatment. Methods Selected 80 cases treated by nasal endoscopic repair of cerebrospinal fluid rhinorrhea from January 2010 to 2015 as study object, ret-rospective analyzed the clinical data such as the patient's age, gender, etiology, leak size, the leak location, prior in-tracranial infection, prophylactic antibiotics and postoperative application of antibacterial drug > 7 d, the number of operations, whether or not the operation using artificial materials, repair materials, repair of cerebrospinal fluid rhin-orrhea failure and by nasal endoscopic repair of cerebrospinal fluid rhinorrhea occurred between intracranial infec-tion. Results 4 of them (5.00 %) occurred intracranial infection. CSF bacterial culture show 8 strains of pathogenic bacteria were isolated, including 3 cases of leather of gram negative bacteria and 5 strains of leather of gram positive bacteria and gram positive bacteria were mainly Staphylococcus aureus and accounted for 40.00 %. Univariate anal-ysis showed that repair of cerebrospinal fluid rhinorrhea failure, improper surgical procedures, previous intracranial infection history, the choice of restorative materials and the size of the leak diameter > 1 cm and after endoscopic repair of cerebrospinal fluid rhinorrhea postoperative intracranial infection have some relevance ( < 0.05). Logistic multivariate analysis showed that repair of cerebrospinal fluid rhinorrhea failure, improper surgical procedures, previ-ous intracranial infection history, the choice of restorative materials and the size of the leak diameter > 1 cm of intranasal endoscopic repair of cerebrospinal fluid rhinorrhea independent risk factor for postoperative intracranial infection ( < 0.05). Conclusions Skull size of the leak diameter > 1 cm, previous history of intracranial infection, cerebrospinal fluid rhinorrhea repair a variety of factors fail, surgery failure factors are likely to increase patient after endoscopic repair of cerebrospinal fluid rhinorrhea intracranial infection the incidence.
