Impact of Dezocine on anesthesia recovery and postoperative pain in children receiving laparoscopic appendectomy
10.3969/j.issn.1007-1989.2016.07.006
- VernacularTitle:地佐辛对小儿腹腔镜阑尾术后苏醒及镇痛的影响
- Author:
Zheng HU
;
Jianshe WANG
;
Longde ZHAO
;
Meimin QU
- Keywords:
Dezocine;
children;
laparoscopic surgery;
postoperative pain;
anesthesia recovery
- From:
China Journal of Endoscopy
2016;22(7):22-25
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the impact of Dezocine used before end of operation on postoperative recovery and safety effect on postoperative pain in children receiving laparoscopic appendectomy. Methods 60 ASAⅠ ~ Ⅱcases of aged 4~10 yr, underwent laparoscopic appendectomy, were randomly divided into 3 groups: Dezocine group (D group), Fentanyl group (F group) and control group (normal saline group), 20 cases in each group. Remifentanil combined with Propofol and Sevoflurane was given for conducting endotracheal intubation general anesthesia. At 30 min before the end of operation, D group was given Dezocine 0.10 mg/kg, while F group fentanyl 1.0 μg/kg, and the control group was given same volume of normal saline. 5 min before the end of the operation anesthetics disabled, then extubation until children open eyes on call and spontaneous breathing recovered satisfactorily. Observe and record MAP, HR, SPO2 and respiration rate (RR) at different times:drug withdrawal, extubation and 5 min after ex﹣tubation, while also record extubation time, Riker sedation-agitation scores and face, legs, activity, cry and consola﹣bility (FLACC) scores and adverse reactions in the recovery period (within 30 min after extubation). Results MAP and HR at extubation and 5 min after extubation in N group and F group were higher than that in D group (P<0.05);Compared with drug withdrawal time, HR and MAP at extubation and 5 min after extubation in group F and N were much higher (P< 0.05); MAP, HR, SPO2 and RR had no statistically significant difference in D group at each time point (P> 0.05). The Riker sedation-agitation scores and the FLACC scores at 30 min after extubation in D group were significantly lower than those in the F and N groups (P<0.05), adverse reaction such as respiratory inhi﹣bition, nausea, vomiting, lethargy, headache were not found in the 3 groups. Conclusion Intravenous Dezocine before the end of operation in children's laparoscopic operation can make awake quickly and smoothly, allow small hemo﹣dynamic changes, and can reduce postoperative pain and restlessness.
